Soy Phospholipid (Lipoid S 75) in Liposome and mRNA Formulation: Uses and Development Considerations
The performance of an mRNA formulation depends on more than the quality of the encoded sequence. Although mRNA design, nucleotide modification, capping, and polyadenylation strongly influence stability and translation, the delivery system ultimately determines whether the transcript can remain intact, reach the intended cells, enter the cytoplasm, and produce the desired protein.
This has made...